Browsing by Author "Abdik, Ezgi Avsar"
Now showing items 1-4 of 4
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Dual Akt and Bcl-2 inhibition induces cell-type specific modulation of apoptotic and autophagic signaling in castration resistant prostate cancer cell lines
Abdik, Ezgi Avsar; Abdik, Huseyin; Turan, Duygu; Sahin, Fikrettin; Berger, Martin R.; Kaleagasioglu, Ferda (Springer, 2021)Background Cancer cell survival depends on the cross-regulation between apoptosis and autophagy which share common signaling pathways including PI3K/Akt/mTOR and Bcl-2. The aim of this study was to elucidate the modulation ... -
Evaluation of the neuroprotective potential of caffeic acid phenethyl ester in a cellular model of Parkinson's disease
Turan, Duygu; Abdik, Hüseyin; Sahin, Fikrettin; Abdik, Ezgi Avsar (Elsevier, 2020)Parkinson's disease (PD) is the second most prevalent neurodegenerative disease, and oxidative stress and mitochondrial dysfunction play a major role in the pathogenesis of PD. Since conventional therapeutics are not ... -
Grapefruit-derived extracellular vesicles as a promising cell-free therapeutic tool for wound healing
Savci, Yagiz; Kirbas, Oguz Kaan; Bozkurt, Batuhan Turhan; Abdik, Ezgi Avsar; Tasli, Pakize Neslihan; Sahin, Fikrettin; Abdik, Huseyin (Royal Soc Chemistry, 2021)Due to the prevalence of individuals suffering from chronic wounds, developing safe and effective wound care agents are one of the more prominent fields of research in biology. However, wound healing is a complex, multi-stage ... -
Sodium Pentaborate Pentahydrate ameliorates lipid accumulation and pathological damage caused by high fat diet induced obesity in BALB/ c mice
Abdik, Huseyin; Cumbul, Alev; Hayal, Taha Bartu; Abdik, Ezgi Avsar; Tasli, Pakize Neslihan; Kirbas, Oguz Kaan; Sahin, Fikrettin (Elsevier Gmbh, 2021)Background: Obesity is one of the most popular topic in the field of research. In order to defeat this highly widespread disease, the mechanism of fat accumulation at the molecular level and its elimination are crucial. ...
