Browsing by Author "Abdik, Huseyin"
Now showing items 1-4 of 4
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Antineoplastic effects of erufosine on small cell and non-small cell lung cancer cells through induction of apoptosis and cell cycle arrest
Abdik, Huseyin (Springer, 2022)Background Lung cancer (LC) is the most common types of cancer worldwide and is marked by high mortality rate. LC is classified into two major types due to their molecular and histological properties; non-small cell lung ... -
Dual Akt and Bcl-2 inhibition induces cell-type specific modulation of apoptotic and autophagic signaling in castration resistant prostate cancer cell lines
Abdik, Ezgi Avsar; Abdik, Huseyin; Turan, Duygu; Sahin, Fikrettin; Berger, Martin R.; Kaleagasioglu, Ferda (Springer, 2021)Background Cancer cell survival depends on the cross-regulation between apoptosis and autophagy which share common signaling pathways including PI3K/Akt/mTOR and Bcl-2. The aim of this study was to elucidate the modulation ... -
Grapefruit-derived extracellular vesicles as a promising cell-free therapeutic tool for wound healing
Savci, Yagiz; Kirbas, Oguz Kaan; Bozkurt, Batuhan Turhan; Abdik, Ezgi Avsar; Tasli, Pakize Neslihan; Sahin, Fikrettin; Abdik, Huseyin (Royal Soc Chemistry, 2021)Due to the prevalence of individuals suffering from chronic wounds, developing safe and effective wound care agents are one of the more prominent fields of research in biology. However, wound healing is a complex, multi-stage ... -
Sodium Pentaborate Pentahydrate ameliorates lipid accumulation and pathological damage caused by high fat diet induced obesity in BALB/ c mice
Abdik, Huseyin; Cumbul, Alev; Hayal, Taha Bartu; Abdik, Ezgi Avsar; Tasli, Pakize Neslihan; Kirbas, Oguz Kaan; Sahin, Fikrettin (Elsevier Gmbh, 2021)Background: Obesity is one of the most popular topic in the field of research. In order to defeat this highly widespread disease, the mechanism of fat accumulation at the molecular level and its elimination are crucial. ...