Browsing by Author "Bolat, Zeynep Büşra"
Now showing items 1-8 of 8
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The Anti-proliferative Effect of Caffeic Acid and Dactolisib on Human Cervical Carcinoma HeLa Cell Line
Bolat, Zeynep Büşra (Sivas Cumhuriyet Üniversitesi, 2024)Cervical carcinoma is a common gynecological cancer with high mortality rate among women worldwide. Caffeic acid exerts an antiproliferative effect against cervical carcinoma. Dactolisib is a dual PI3K and mTOR inhibitor that ... -
Development of Peptide-18-Targeted Nanoliposome Formulations With an Alternative Stealth Coating Copolymer for Targeting Breast Cancer AU565 Cell Line
Saka, Ongun Mehmet; Bolat, Zeynep Büşra; Telci, Dilek; Şahin, Fikrettin; Gülyüz, Sevgi; Özköse, Umut Uğur; Yılmaz, Özgür; Bozkır, Asuman (John Wiley and Sons Ltd, 2024)The incidence of breast cancer has increased considerably in recent years. Many efforts have been made to develop various nano-drug delivery systems with specific properties to achieve effective and specific therapy. The ... -
Integrated transcriptome and in vitro analysis revealed anti-proliferative effect of sodium perborate on hepatocellular carcinoma cells
Ömeroğlu Ulu, Zehra; Bolat, Zeynep Büşra; Şahin, Fikrettin (Elsevier GmbH, 2022)Background: Hepatocelular carcinoma is one of the leading cancer types with no effective cure as poor prognosis is still a challenging aspect. Thus, alternative therapeutics are necessary to control hepatocelular carcinoma. ... -
Synergistic Anti-Cancer Effect of Sodium Pentaborate Pentahydrate, Curcumin and Piperine on Hepatocellular Carcinoma Cells
Ömeroğlu Ulu, Zehra; Değirmenci, Nurdan Sena; Bolat, Zeynep Büşra; Şahin, Fikrettin (Nature Research, 2023)Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death in the world. Poor prognosis of HCC patients is a major issue, thus, better treatment options for patients are required. Curcumin (Cur), hydrophobic ... -
Synergistic Anti‑Proliferative and Apoptotic Effect of NVP‑BEZ235 and Curcumin on Human SH‑SY5Y Neuroblastoma Cells
Çetin, Fadime; Kosba, Şifa; Abdik, Hüseyin; Bolat, Zeynep Büşra (Springer, 2023)Neuroblastoma, a tumor of the sympathetic nervous system, is one of the most common tumors found in children. Most patients develop resistance to therapy and show poor prognosis, thus there is a need of novel therapeutic ... -
Synthesis, biocompatibility and gene encapsulation of poly(2-Ethyl 2-Oxazoline)-dioleoyl phosphatidylethanolamine (PEtOx-DOPE) and post-modifications with peptides and fluorescent dye coumarin
Gulyuz, Sevgi; Bayram, Duygu; Ozkose, Umut Ugur; Bolat, Zeynep Büşra; Kocak, Polen; Saka, Ongun Mehmet; Yilmaz, Ozgur (Taylor & Francis As, 2020)Liposome surface modifications serve great potential applications of liposomes, for instance, increasing stability, bioactive liposome conjugates, and targeted drug, gene, and image agent delivery. In this study, novel ... -
Targeting Prostate Cancer with Docetaxel-Loaded Peptide 563-Conjugated PEtOx-Co-PEI30%-B-PCL Polymeric Micelle Nanocarriers
Nezir, Ayca Ece; Bolat, Zeynep Büşra; Öztürk, Naile; Koçak, Pelin; Zemheri, Itır Ebru; Gülyüz, Sevgi; Özköse, Umut Uğur; Yılmaz, Özgür; Vural, İmran; Bozkır, Asuman; Şahin, Fikrettin; Telci, Dilek (Springer, 2023)Prostate cancer is a global disease that negatively affects the quality of life. Although various strategies against prostate cancer have been developed, only a few achieved tumor-specific targeting. Therefore, a special ... -
The utilization of poly(2-ethyl-2-oxazoline)-b-poly(epsilon-caprolactone) ellipsoidal particles for intracellular BIKDDA delivery to prostate cancer
Kocak, Polen; Oz, Umut Can; Bolat, Zeynep Büşra; Ozkose, Umut Ugur; Gulyuz, Sevgi; Tasdelen, Mehmet Atilla; Telci, Dilek (Wiley-V C H Verlag Gmbh, 2020)Prostate cancer is the most common cancer, which is about 15-20% among male cancers worldwide. As most common strategies such as radiotherapy, chemotherapy, or surgery alone can be unsuccessful in the treatment of prostate ...
