Browsing by Author "Gülseren, İbrahim"
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5-fluorouracil release from sunflower pectin hydrogels in simulated intestinal medium and its corresponding anti-carcinogenic activity
Çakır, Bilal; Gülseren, İbrahim (Association of Indian Pharmacist, 2017)5-fluorouacil (5-FU) is a commonly used medication in the treatment of cancers including colon, stomach, pancreatic and breast cancers. In this study, 5-FU was encapsulated in low methoxyl sunflower pectin (i.e., sunflower ... -
Antioxidative activities of hazelnut protein hydrolyzates as predicted by in silico analysis techniques
Gülseren, İbrahim (2019)Recently, a variety of studies have been carried out on the production and analysis ofbioactive peptides. Here, based on in silico methods, antioxidative behavior of hazelnut(Corylus avellana L.) peptides, which could be ... -
Ayçiçeği pektiniyle enkapsüle edilen hidrofilik ve lipofilik kırmızı renklendiricilerin hidrojel ve emülsiyon hidrojellerindeki stabilitesi
Coşkun, Özgenur; Gülseren, İbrahim (2018)Hidrojeller ve parçacık içeren hidrojeller (emülsiyon jelleri), hidrofilik ve lipofilikboyaların enkapsülasyonunda kullanıma uygunluk arz eden enkapsülasyonsistemleridir. Bu çalışmada, ayçiçeği pektini bazlı hidrojellerde ... -
Bitkisel yağ olarak değerlendirilebilen yağlı tohum ve meyvelerin posalarından protein konsantresi ve izolatlarının üretilmesi ve bunların değerlendirilmesi
Bu projede uygun sulu ve organik ekstraksiyon yöntemleri kullanılarak soğuk pres posalarından protein konsantreleri üretimi gerçekleştirilmiştir. Bu bağlamda kullanılan başlıca numuneler arasında çörek otu, kabak çekirdeği, ... -
Delivery of curcumin using skim milk or oil in water emulsions: effect of the matrices on cellular uptake
Guri, Anilda; Gülseren, İbrahim; Arranz, Elena; Corredig, Milena (JAPAN OIL CHEMISTS SOC, 2018)To enhance the curcumin delivery in a variety of food grade matrices namely spray dried ethanolic curcumin in fresh skim milk (Spray dried Cu-SM), a fresh mixture of ethanolic curcumin and skim milk (Fresh Cu-SM) a powder ... -
Dissolution kinetics of polyphenol bearing calcium pectate hydrogels in simulated gastric or intestinal media and their anti-carcinogenic capacities
Cakır, Bilal; Gülseren, İbrahim (ELSEVIER SCI LTD, 2017)Cherry laurel is an underutilized agricultural resource with a significant content of polyphenolic compounds that potentially may demonstrate antioxidant and anti-carcinogenic activities. In this study, the preparation of ... -
Effect of interfacial composition on uptake of curcumin-piperine mixtures in oil in water emulsions by Caco-2 cells
Gülseren, İbrahim; Guri, Anilda; Corredig, Milena (Royal Society of Chemistry, 2014)Encapsulation in lipid particles is often proposed as a solution to improve curcumin bioavailability. This bioactive molecule has low water solubility and rapidly degrades during digestion. In the present study, the uptake ... -
Effect of processing on physicochemical characteristics and bioefficacy of β-lactoglobulin-epigallocatechin-3-gallate complexes
Lestringant, P.; Guri, A.; Gülseren, İbrahim; Relkin, P.; Corredig, M. (American Chemical Society, 2014)Varying amounts of epigallocatechin-3-gallate (EGCG) were encapsulated in β-lactoglobulin (β-Lg) nanoparticles, either native or processed, denoted as heated or desolvated protein. The stability, physical properties, and ... -
Food nanotechnology applications to the beverage industry
Arranz, Elena; Gülseren, İbrahim; Corredig, Milena; Guri, Anilda (CRC Press, 2019)Health-conscious consumers are looking for foods that impart benefits beyond simple nutrition. Beverages are seen by consumers as the most active food category for their convenience in usage and distribution, and they have ... -
Identification of Novel Proteins from Black Cumin Seed Meals Based on 2D Gel Electrophoresis and MALDI-TOF/TOF-MS Analysis
Çakir, Bilal; Gülseren, İbrahim (Springer New York LLC, 2019)The amount of cold press oil manufacture is globally rising, which in turn leads to the accumulation of deoiled plant seeds at significant quantities and consequent manufacture of plant protein products. In this study, we ... -
In silico methods to identify ACE and DPP-IV inhibitory activities of ribosomal hazelnut proteins
Gülseren, İbrahim (Springer, 2018)In this study, an in silico attempt was made to evaluate the biological functionality of hazelnut (Corylus avellana L.) peptides, using three gastrointestinal (GI) and three non-GI enzymes. As of March 2017, 469 hazelnut ... -
Influence of extraction conditions on structural and functional characteristics of black cumin protein concentrates and ACE-inhibition in their hydrolyzates
Coşkun, Özgenur; Çakır, Bilal; Vahapoğlu, Beyza; Gülseren, İbrahim (Springer Verlag, 2019)Cold press oils are value-added food ingredients that are increasingly produced. Due to the removal of oil, protein content in cold press deoiled meals substantially increase. Here, we made an attempt to manufacture protein ... -
Influence of Maillard reaction conditions and solvent extraction on the surface activity and foaming characteristics of black cumin protein concentrates
Coşkun, Özgenur; Çağlar, Ahmet Furkan; Çakır, Bilal; Gülseren, İbrahim (Springer, 2020)Cold press manufacture of black cumin (BC) oil leads to the formation of BC press cakes that contain significant amounts of protein. Here, an attempt was made to enhance the functionality of BC protein concentrates obtained ... -
Influence of phenolic profile on the RP-HPLC detection and anti-carcinogenic potential of cherry laurel extracts from Black Sea Region-Turkey
Bayrambaş, Kadir; Çakır, Bilal; Gülseren, İbrahim (Elsevier Inc., 2019)Cherry laurel produces edible dark colored fruits that are anticipated to have strongly antioxidative properties. Various studies dealt with the phenolic composition of cherry laurel fruits or concentrated juice to analyze ... -
Investigations on apoptotic activities of cherry laurel extracts in HCT-116 human colon carcinoma cells
Çakır, Bilal; Gülseren, İbrahim (Assoc Pharmaceutical Teachers India, 2019)Background: Cherry laurel fruits are characterized by their dark color and rich phenolic contents. Previously, phenolic extracts from cherry laurel varieties were shown to demonstrate anti-proliferative activities against ... -
KARAYEMİŞ MEYVESİNİN BİYOAKTİF ÖZELLİKLERİ VE FONKSİYONEL GIDALARDA KULLANIM POTANSİYELİ
Karayemiş, besin değeri yüksek olan bir meyvedir. Bünyesinde değerli yağ asitleri, organik asitler ve mineralmaddeler bulundurmaktadır. İçerdiği fenolik bileşikler ve bu bileşiklerin ortaya çıkardığı yüksek antioksidatifkapasite, ... -
Kayısı tohum ve depo protein hidrolizatlarının antihipertansif ve antidiyabetik özelliklerinin in silico analizi
Yafez, Mehmet Ali (İstanbul Sabahattin Zaim Üniversitesi, 2021)Ülkemizde dolaşım sistemi hastalıkları ölüm sebeplerinde birinci sıradadır. Türkiye İstatistik Kurumu (TÜİK) verilerine göre 2019 yılında gerçekleşen ölümlerin %36.6'sı dolaşım sistemi hastalıkları sebebi ile gerçekleşmiştir. ... -
Linking collective in vitro to individual in silico peptide bioactivity through mass spectrometry (LC-Q-TOF/MS) based sequence identification: the case of black cumin protein hydrolysates
Zent, İnci; Göksu, Ayşe Gülden; Çakır, Bilal; Gülseren, İbrahim (Springer, 2020)Abstract: Black cumin (Nigella sativa L.) is a seed that has been utilized in traditional medicine due to the bioactive characteristics of seed oil and therein solubilized components. In the present study, using enzymatic ... -
Nanoencapsulation of Enzymes, Bioactive Peptides, and Biological Molecules
Çağlar, Muhammed Yusuf; Demirci, Mehmet; Bayrambas, Kadir; Çakır, Bilal; Gülseren, İbrahim (ACADEMIC PRESS LTD-ELSEVIER SCIENCE LTD, 2017)Nanoencapsulation systems that bear enzymes, proteins, bioactive peptides, and biological molecules are among the most commonly investigated delivery systems in food and nutraceuticals research. Although the majority of ... -
Nanofibrils of beta-lactoglobulin for encapsulation of food ingredients
Coşkun, Özgenur; Gülseren, İbrahim (Elsevier, 2019)β-Lactoglobulin (β-LG) constitutes approximately 10% of all the milk proteins becoming the major whey protein. β-LG nanofibrils (β-LG-N) have been prepared as based on various physicochemical or enzymatic processes. ...
