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dc.contributor.authorÇınar, F.
dc.contributor.authorEkinci, G.
dc.date.accessioned2022-03-04T19:12:36Z
dc.date.available2022-03-04T19:12:36Z
dc.date.issued2022
dc.identifier.issn2069-5837
dc.identifier.urihttps://doi.org/10.33263/BRIAC124.55795590
dc.identifier.urihttps://hdl.handle.net/20.500.12436/3255
dc.description.abstractComorbidity is the coexistence of two or more diseases in a certain period. Severe COVID-19 can occur in healthy individuals of any age but predominantly in adults of advanced age or with underlying medical comorbidity. Comorbidities are identified as the main determinants of poor outcomes. This meta-analysis aims to examine the effect of comorbidity on mortality in patients with a diagnosis of COVID-19. Materials and Methods: The studies published between 2019-2020 from Google Scholar, Pub Med, Medline, Scopus, Science Direct, and Web of Science databases were scanned. Interrater agreement was calculated with Kappa statistics, effect size "Odds Ratio", heterogeneity between studies with Cochran's Q statistics. The study's effect size and publication bias included in the meta-analysis were calculated using the CMA 3 (Comprehensive Meta-Analysis) program. Results: A total of 24 studies were included in the study. According to the random-effects model, the overall effect size of comorbid factors on mortality development in patients diagnosed with COVID-19 was found to be statistically significant with a value of 2.537 (G.A; 2.078-2.098; p <0.05). In conclusion, cancers, chronic respiratory diseases, diabetes, hypertension, and especially cardiovascular comorbidities are important risk factors for COVID-19 related mortality for COVID-19. There are controversial results in the literature; Further studies involving larger patient groups and examining the specific impact of certain comorbid conditions are needed in order to reach more precise conclusions. © 2021 by the authors.en_US
dc.language.isoengen_US
dc.publisherAMG Transcend Associationen_US
dc.relation.ispartofBiointerface Research in Applied Chemistryen_US
dc.identifier.doi10.33263/BRIAC124.55795590
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectComorbidityen_US
dc.subjectCOVİD-19en_US
dc.subjectMortalityen_US
dc.titleInvestigation of the effect of comorbidity on mortality in patients with covid-19: A systematic review and meta-analysisen_US
dc.typearticleen_US
dc.departmentİZÜen_US
dc.identifier.volume12en_US
dc.identifier.issue4en_US
dc.identifier.startpage5579en_US
dc.identifier.endpage5590en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.department-tempÇınar, F., Nisantasi Üniversity, İstanbul, Turkey; Ekinci, G., Sabahattin Zaim University, İstanbul, Turkeyen_US
dc.authorscopusid57204505449
dc.authorscopusid57300453600
dc.identifier.scopus2-s2.0-85117366175en_US


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