Antibacterial and cellular behavior of PLA-based bacitracin and zataria multiflora nanofibers produced by electrospinning method

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dc.authorscopusid57218222258
dc.authorscopusid45960896500
dc.authorscopusid57223867999
dc.authorscopusid12797373800
dc.authorscopusid9233321100
dc.authorwosidGunduz, Oguzhan/E-5292-2011
dc.contributor.authorCiftci, Fatih
dc.contributor.authorDuygulu, Nilufer
dc.contributor.authorYilmazer, Yasemin
dc.contributor.authorGunduz, Oguzhan
dc.contributor.authorUstundag, Cem Bulent
dc.date.accessioned2022-03-04T19:12:24Z
dc.date.available2022-03-04T19:12:24Z
dc.date.issued2021
dc.departmentİZÜen_US
dc.description.abstractIn this study, poly(lactic-acid) (PLA) polymer-based nanofiber (NF) was obtained by the electrospinning method. Antioxidant Zataria Multiflora (ZM, essential oil extract) and antibiotic effective bacitracin (BAC) materials were added to 8% PLA. ZM essential oil was extracted with Rotary and antioxidant components were investigated using GC-MS. While carvacrol constitutes 50% as the main component of ZM, it was seen as 48.06% carvacrol and 25.47% thymol as a content area. It was analyzed that ZM has a total antioxidant rate of 99.87% with 20 components. In antibacterial tests, PLA/BAC/ZM NF showed the best inhibition growth on all microorganisms (Escherichia coli, Staphylococcus aureus, Bacillus cereus, Staphylococcus epidermidis, Bacillus subtilis). In cell XTT cytotoxicity tests, it was observed that the PLA/BAC/ZM NF used in adhesion and 4 ',6-diamidino-2-phenylindole (DAPI) results showed very good adhesion to cells.en_US
dc.description.sponsorshipYildiz Technical University Scientific Research Projects Coordination DepartmentYildiz Technical University [FDK-2019-3531]en_US
dc.description.sponsorshipThe work has been supported by the Yildiz Technical University Scientific Research Projects Coordination Department. The project number is FDK-2019-3531.en_US
dc.identifier.doi10.1080/00914037.2021.2008391
dc.identifier.issn0091-4037
dc.identifier.issn1563-535X
dc.identifier.orcidUstundag, Cem/0000-0002-4439-0878
dc.identifier.orcidCiftci, Fatih/0000-0002-3062-2404
dc.identifier.orcidGunduz, Oguzhan/0000-0002-9427-7574
dc.identifier.scopus2-s2.0-85121366755en_US
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1080/00914037.2021.2008391
dc.identifier.urihttps://hdl.handle.net/20.500.12436/3185
dc.identifier.wosWOS:000728152600001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherTaylor & Francis Asen_US
dc.relation.ispartofInternational Journal of Polymeric Materials and Polymeric Biomaterialsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntioxidanten_US
dc.subjectcarvacrolen_US
dc.subjectdrugen_US
dc.subjectelectrospinningen_US
dc.subjectessential oilen_US
dc.subjectpolymer nanofiberen_US
dc.subjectthymolen_US
dc.subjectESSENTIAL OILen_US
dc.subjectIN-VITROen_US
dc.subjectANTIOXIDANTen_US
dc.subjectEXTRACTen_US
dc.subjectGROWTHen_US
dc.subjectBOISS.en_US
dc.titleAntibacterial and cellular behavior of PLA-based bacitracin and zataria multiflora nanofibers produced by electrospinning methoden_US
dc.typeArticle
dspace.entity.typePublication

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